Analysis of IFITM-IFITM Interactions by a Flow Cytometry-Based FRET Assay

The interferon-induced transmembrane proteins 1−3 (IFITM1−3) inhibit host cell entry of several viruses. However, it is incompletely understood how IFITM1−3 exert antiviral activity. Two phenylalanine residues, F75 and F78, within the intramembrane domain 1 (IM1) were p...

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Bibliographic Details
Main Authors: Michael Winkler, Florian Wrensch, Pascale Bosch, Maike Knoth, Michael Schindler, Sabine Gärtner, Stefan Pöhlmann
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
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Online Access:https://www.mdpi.com/1422-0067/20/16/3859