Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells

Modeling congenital cataract in vitro using patient-specific induced pluripotent stem cells

Abstract Congenital cataracts are the leading cause of childhood blindness. To date, surgical removal of cataracts is the only established treatment, but surgery is associated with multiple complications, which often lead to visual impairment. Therefore, mechanistic studies and drug-candidate screen...

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Bibliographic Details
Main Authors: Danni Lyu, Lifang Zhang, Zhenwei Qin, Shuang Ni, Jiayong Li, Bing Lu, Shengjie Hao, Qiaomei Tang, Houfa Yin, Zhijian Chen, Yong-Bin Yan, Junfeng Ji, Jiliang He, Andras Nagy, Qiuli Fu, Ke Yao
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00171-x

Internet

https://doi.org/10.1038/s41536-021-00171-x

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