Peroxiredoxin I deficiency attenuates phagocytic capacity of macrophage in clearance of the red blood cells damaged by oxidative stress

Peroxiredoxin I deficiency attenuates phagocytic capacity of macrophage in clearance of the red blood cells damaged by oxidative stress

The role of peroxiredoxin (Prx) I as an erythrocyte antioxidantdefense in red blood cells (RBCs) is controversial. Here weinvestigated the function of Prx I by using Prx I–⁄– and Prx I/II–⁄–mice. Prx I–⁄– mice exhibited a normal blood profile. However,Prx I/II–⁄– mice showed more significantly incre...

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Bibliographic Details
Main Author: Ying-Hao Han1,8,#, Taeho Kwon1,7,#, Sun-Uk Kim1,2,#, Hye-Lin Ha1, Tae-Hoon Lee1,3, Jin-Man Kim4, Eun-Kyeong Jo5, Bo Yeon Kim6, Do Young Yoon7 & Dae-Yeul Yu1,*
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012-10-01
Series:BMB Reports
Subjects:
Heinz body
Hemolytic anemia
Macrophage
Peroxiredoxin
Phagocytosis
Online Access:http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTIyMTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS0xMCU1RDEyMTAyOTIxMTVfJTI4NTYwLTU2NCUyOUJNQl8xMi0wODIucGRm

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http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTIyMTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS0xMCU1RDEyMTAyOTIxMTVfJTI4NTYwLTU2NCUyOUJNQl8xMi0wODIucGRm

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