Fibronectin Type III Domain-Containing 5 Attenuates Liver Fibrosis Via Inhibition of Hepatic Stellate Cell Activation

Fibronectin Type III Domain-Containing 5 Attenuates Liver Fibrosis Via Inhibition of Hepatic Stellate Cell Activation

Background/Aims: Fibronectin type III domain-containing 5 (FNDC5) protein is involved in the beneficial effects of exercise on metabolism. FNDC5 attenuates hepatic steatosis induced by high fat diet (HFD). Here, we examined the effects of FNDC5 on liver fibrosis and underline mechanisms. Methods: Ex...

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Bibliographic Details
Main Authors: Bing Zhou, Li Ling, Feng Zhang, Tong-Yan Liu, Hong Zhou, Xiao-Hong Qi, Qi Chen, Yue-Hua Li, Yu-Ming Kang, Guo-Qing Zhu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Fndc5
Liver fibrosis
Hepatic stellate cell
Obesity
High fat diet
Online Access:https://www.karger.com/Article/FullText/491722

Internet

https://www.karger.com/Article/FullText/491722

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