Residue Asn277 Affects the Stability and Substrate Specificity of the SMG1 Lipase from Malassezia globosa

Residue Asn277 Affects the Stability and Substrate Specificity of the SMG1 Lipase from Malassezia globosa

Thermostability and substrate specificity are important characteristics of enzymes for industrial application, which can be improved by protein engineering. SMG1 lipase from Malassezia globosa is a mono- and diacylglycerol lipase (MDL) that shows activity toward mono- and diacylglycerols, but no act...

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Bibliographic Details
Main Authors: Dongming Lan, Qian Wang, Jinxin Xu, Pengfei Zhou, Bo Yang, Yonghua Wang
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
mono- and diacylglycerol lipase
thermostability
substrate selectivity
site-directed mutagenesis
Online Access:http://www.mdpi.com/1422-0067/16/4/7273

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http://www.mdpi.com/1422-0067/16/4/7273

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