CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma

Abstract Background Mounting evidence suggests that solid tumors display the features of collective invasion, however, the molecular mechanisms are far from clear. This study aims to verify the role and the underlying mechanisms of CD147 in collective invasion in hepatocellular carcinoma. Methods Im...

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Bibliographic Details
Main Authors: Shi-Jie Wang, Dong Chao, Wei Wei, Gang Nan, Jia-Yue Li, Fen-Ling Liu, Ling Li, Jian-Li Jiang, Hong-Yong Cui, Zhi-Nan Chen
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-020-01647-2