H-NS nucleoid protein controls virulence features of Klebsiella pneumoniae by regulating the expression of type 3 pili and the capsule polysaccharide

Klebsiella pneumoniae is an opportunistic pathogen causing nosocomial infections. Main virulence determinants of K. pneumoniae are pili, capsular polysaccharide, lipopolysaccharide and siderophores. The histone-like nucleoid-structuring protein (H-NS) is a pleiotropic regulator found in several gram...

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Bibliographic Details
Main Authors: Miguel A. eAres, José L. eFernández-Vázquez, Roberto eRosales-Reyes, Ma. Dolores eJarillo-Quijada, Kristine eVon Bargen, Javier eTorres, Jorge A. eGonzález-y-Merchand, María D. eAlcántar-Curiel, Miguel A eDe la Cruz
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
T3P
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00013/full