Patient-Derived In Vitro Models for Drug Discovery in Colorectal Carcinoma

Patient-Derived In Vitro Models for Drug Discovery in Colorectal Carcinoma

Lack of relevant preclinical models that reliably recapitulate the complexity and heterogeneity of human cancer has slowed down the development and approval of new anti-cancer therapies. Even though two-dimensional in vitro culture models remain widely used, they allow only partial cell-to-cell and...

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Bibliographic Details
Main Authors: George M. Ramzy, Thibaud Koessler, Eloise Ducrey, Thomas McKee, Frédéric Ris, Nicolas Buchs, Laura Rubbia-Brandt, Pierre-Yves Dietrich, Patrycja Nowak-Sliwinska
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
Colorectal cancer
organoids
3D bioprinting
patient-derived xenograft
cancer-on-chip
drug combination
Online Access:https://www.mdpi.com/2072-6694/12/6/1423

Internet

https://www.mdpi.com/2072-6694/12/6/1423

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