Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment

Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment

Anti-tuberculosis drug treatment is known to affect the number, phenotype, and effector functionality of antigen-specific T-cells. In order to objectively gauge Mycobacterium tuberculosis (MTB)-specific CD8+ T-cells at the single-cell level, we developed soluble major histocompatibility complex (MH...

Full description

Bibliographic Details
Main Authors: Rebecca Axelsson-Robertson, Martin Rao, Andre G. Loxton, Gerhard Walzl, Matthew Bates, Alimuddin Zumla, Markus Maeurer
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:International Journal of Infectious Diseases
Subjects:
CD8+ T-cells
Mycobacterium tuberculosis
Tetramers
Multimers
MHC
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971215000235

Internet

http://www.sciencedirect.com/science/article/pii/S1201971215000235

Similar Items