Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis

Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis

Cancer immunotherapy is revolutionizing the clinical management of several tumors, but has demonstrated limited activity in breast cancer. The development of more effective treatments is hindered by incomplete knowledge of the genetic determinant of immune responsiveness. To fill this gap, we mined...

Full description

Bibliographic Details
Main Authors: Wouter Hendrickx, Ines Simeone, Samreen Anjum, Younes Mokrab, François Bertucci, Pascal Finetti, Giuseppe Curigliano, Barbara Seliger, Luigi Cerulo, Sara Tomei, Lucia Gemma Delogu, Cristina Maccalli, Ena Wang, Lance D. Miller, Francesco M. Marincola, Michele Ceccarelli, Davide Bedognetti
Format: Article
Language:English
Published: Taylor & Francis Group 2017-02-01
Series:OncoImmunology
Subjects:
breast cancer
chemokines
exome sequencing
immune checkpoint
immune signatures
immunologic constant of rejection
mapk mutations
pd-l1
predictive signatures
prognostic signatures
triple negative
Online Access:http://dx.doi.org/10.1080/2162402X.2016.1253654

Internet

http://dx.doi.org/10.1080/2162402X.2016.1253654

Similar Items