DNA methylation repels targeting of Arabidopsis REF6

DNA methylation repels targeting of Arabidopsis REF6

REF6 is a H3K27me3 histone demethylase that targets regions of active chromatin in the Arabidopsis genome. Here Qiu et al. show that REF6 preferentially binds unmethylated DNA via its zinc-finger domains suggesting that DNA methylation might deter REF6 binding in heterochromatin.

Bibliographic Details
Main Authors: Qi Qiu, Hailiang Mei, Xian Deng, Kaixuan He, Baixing Wu, Qingqing Yao, Jixiang Zhang, Falong Lu, Jinbiao Ma, Xiaofeng Cao
Format: Article
Language:English
Published: Nature Publishing Group 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10026-1

Internet

https://doi.org/10.1038/s41467-019-10026-1

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