Arctiin protects against cardiac hypertrophy through inhibiting MAPKs and AKT signaling pathways

Arctiin protects against cardiac hypertrophy through inhibiting MAPKs and AKT signaling pathways

Purpose: The mitogen-activated protein kinases (MAPKs) and protein kinase B (AKT) pathways have emerged as essential intracellular signaling pathways in eukaryotic cells, particularly as regulators of cardiac hypertrophy. Previous studies indicated that arctiin, an active ingredient of biennial drie...

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Bibliographic Details
Main Authors: Jing Li, Yu-Pei Yuan, Si-Chi Xu, Ning Zhang, Chun-Ru Xu, Chun-Xia Wan, Jie Ren, Xiao-Feng Zeng, Qi-Zhu Tang
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Journal of Pharmacological Sciences
Subjects:
Arctiin
Cardiac hypertrophy
Cardiac fibrosis
MAPKs
AKT
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861317301032

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http://www.sciencedirect.com/science/article/pii/S1347861317301032

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