Targeted therapy of human leukemia xenografts in immunodeficient zebrafish

Abstract Personalized medicine holds tremendous promise for improving safety and efficacy of drug therapies by optimizing treatment regimens. Rapidly developed patient-derived xenografts (pdx) could be a helpful tool for analyzing the effect of drugs against an individual’s tumor by growing the tumo...

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Bibliographic Details
Main Authors: Ranganatha R. Somasagara, Xiaoyan Huang, Chunyu Xu, Jamil Haider, Jonathan S. Serody, Paul M. Armistead, TinChung Leung
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85141-5