Genetic Dissection of Hypertrophic Cardiomyopathy with Myocardial RNA-Seq

Genetic Dissection of Hypertrophic Cardiomyopathy with Myocardial RNA-Seq

Hypertrophic cardiomyopathy (HCM) is an inherited disorder of the myocardium, and pathogenic mutations in the sarcomere genes myosin heavy chain 7 (<i>MYH7</i>) and myosin-binding protein C (<i>MYBPC3</i>) explain 60%–70% of observed clinical cases. The heterogeneity of pheno...

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Bibliographic Details
Main Authors: Jun Gao, John Collyer, Maochun Wang, Fengping Sun, Fuyi Xu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
hypertrophic cardiomyopathy
RNA-seq
pathogenic variants
differential gene expression
gene network
Online Access:https://www.mdpi.com/1422-0067/21/9/3040

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https://www.mdpi.com/1422-0067/21/9/3040

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