A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines

A Convenient One-pot Synthesis of 2,3-Disubstituted Thieno[2,3-d]pyrimidin-4(3H)-ones from 2H-Thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, Aromatic Aldehydes and Amines

Abstract An efficient, simple protocol has been established for convenient synthesis of novel 2,3-disubstituted thieno[2,3-d]pyrimidin-4(3H)-one derivatives in good to high yields through a one-pot, two-step and three-component reaction from 2H-thieno[2,3-d][1,3]oxazine-2,4(1H)-diones, aromatic alde...

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Bibliographic Details
Main Authors: Feize Liu, Xueling Hou, Li Fei Nie, Khurshed Bozorov, Michael Decker, Guozheng Huang
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2018-04-01
Series:SynOpen
Subjects:
thieno[2,3-d]pyrimidin-4(3h)-one
one-pot synthesis
intramolecular cyclization
pyrimidinone
quinazolinone
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1610157

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1610157

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