Three Small Molecule Entities (MPK18, MPK334 and YAK308) with Activity against <i>Haemonchus contortus</i> In Vitro

Three Small Molecule Entities (MPK18, MPK334 and YAK308) with Activity against <i>Haemonchus contortus</i> In Vitro

Due to widespread multi-drug resistance in parasitic nematodes of livestock animals, there is an urgent need to discover new anthelmintics with distinct mechanisms of action. Extending previous work, here we screened a panel of 245 chemically-diverse small molecules for anti-parasitic activity again...

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Bibliographic Details
Main Authors: Aya C. Taki, Abdul Jabbar, Thomas Kurz, Beate Lungerich, Guangxu Ma, Joseph J. Byrne, Marc Pflieger, Yodita Asfaha, Fabian Fischer, Bill C. H. Chang, Brad E. Sleebs, Robin B. Gasser
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
<i>Haemonchus contortus</i>
phenotypic screening
anthelmintics
small molecules
Online Access:https://www.mdpi.com/1420-3049/26/9/2819

Internet

https://www.mdpi.com/1420-3049/26/9/2819

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