Chondroitin Sulfate in USA Dietary Supplements in Comparison to Pharma Grade Products: Analytical Fingerprint and Potential Anti-Inflammatory Effect on Human Osteoartritic Chondrocytes and Synoviocytes

Chondroitin Sulfate in USA Dietary Supplements in Comparison to Pharma Grade Products: Analytical Fingerprint and Potential Anti-Inflammatory Effect on Human Osteoartritic Chondrocytes and Synoviocytes

The biological activity of chondroitin sulfate (CS) and glucosamine (GlcN) food supplements (FS), sold in USA against osteoarthritis, might depend on the effective CS and GlcN contents and on the CS structural characteristics. In this paper three USA FS were compared to two pharmaceutical products (...

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Bibliographic Details
Main Authors: Antonietta Stellavato, Odile Francesca Restaino, Valentina Vassallo, Elisabetta Cassese, Rosario Finamore, Carlo Ruosi, Chiara Schiraldi
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceutics
Subjects:
food supplements (FS)
pharmaceutical grade CS
anion exchange chromatography (HPAE-PAD)
capillary electrophoresis (HPCE)
size exclusion chromatography (SEC-TDA)
human primary cells of pathological joints
Online Access:https://www.mdpi.com/1999-4923/13/5/737

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https://www.mdpi.com/1999-4923/13/5/737

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