A Novel Dual Drug Approach that Combines Ivermectin and Dihydromyricetin (DHM) to Reduce Alcohol Drinking and Preference in Mice

A Novel Dual Drug Approach that Combines Ivermectin and Dihydromyricetin (DHM) to Reduce Alcohol Drinking and Preference in Mice

Alcohol use disorder (AUD) affects over 18 million people in the US. Unfortunately, pharmacotherapies available for AUD have limited clinical success and are under prescribed. Previously, we established that avermectin compounds (ivermectin [IVM] and moxidectin) reduce alcohol (ethanol/EtOH) consump...

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Bibliographic Details
Main Authors: Joshua Silva, Eileen Carry, Chen Xue, Jifeng Zhang, Jing Liang, Jacques Y. Roberge, Daryl L. Davies
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
dihydromyricetin
flavonoids
alcohol
alcohol use disorder
ivermectin
Online Access:https://www.mdpi.com/1420-3049/26/6/1791

Internet

https://www.mdpi.com/1420-3049/26/6/1791

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