Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development.

Transcription factors that drive complex patterns of gene expression during animal development bind to thousands of genomic regions, with quantitative differences in binding across bound regions mediating their activity. While we now have tools to characterize the DNA affinities of these proteins an...

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Bibliographic Details
Main Authors: Tommy Kaplan, Xiao-Yong Li, Peter J Sabo, Sean Thomas, John A Stamatoyannopoulos, Mark D Biggin, Michael B Eisen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Genetics
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21304941/?tool=EBI