Carbon monoxide improves cardiac function and mitochondrial population quality in a mouse model of metabolic syndrome.

<h4>Aims</h4>Metabolic syndrome induces cardiac dysfunction associated with mitochondria abnormalities. As low levels of carbon monoxide (CO) may improve myocardial and mitochondrial activities, we tested whether a CO-releasing molecule (CORM-3) reverses metabolic syndrome-induced cardia...

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Main Authors: Steve Lancel, David Montaigne, Xavier Marechal, Camille Marciniak, Sidi Mohamed Hassoun, Brigitte Decoster, Caroline Ballot, Caroline Blazejewski, Delphine Corseaux, Bernadette Lescure, Roberto Motterlini, Remi Neviere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22870253/pdf/?tool=EBI