Synthesis and Biological Activities of Ethyl 2-(2-pyridylacetate) Derivatives Containing Thiourea, 1,2,4-triazole, Thiadiazole and Oxadiazole Moieties

Synthesis and Biological Activities of Ethyl 2-(2-pyridylacetate) Derivatives Containing Thiourea, 1,2,4-triazole, Thiadiazole and Oxadiazole Moieties

Thirty six novel heterocyclic derivatives of ethyl 2-(2-pyridylacetate) were efficiently synthesized. The new compounds involve the linkage of a 2-pyridyl ring with thiosemicarbazide (compounds 1–7), 1,2,4-triazole (compounds 1a–7a), 1,3,4-thiadiazole (compounds 1b–7b), and 1,3,4-oxadiazole (compoun...

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Bibliographic Details
Main Authors: Daniel Szulczyk, Piotr Tomaszewski, Michał Jóźwiak, Anna E. Kozioł, Tadeusz Lis, David Collu, Filippo Iuliano, Marta Struga
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Molecules
Subjects:
1,2,4-triazole
1,3,4-thiadiazole
1,3,4-oxadiazole
thiourea
X-ray crystal structure analysis
biological activity
Online Access:http://www.mdpi.com/1420-3049/22/3/409

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http://www.mdpi.com/1420-3049/22/3/409

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