Cyp3a11 is not essential for the formation of murine bile acids

Humans and mice differ substantially in their bile acid profiles as mice in addition to cholic acid (CA) predominantly synthesize 6β-hydroxylated muricholic acids (MCAs) whereas humans produces chenodeoxycholic acid (CDCA) and CA as primary bile acids. Identifying the gene performing 6β-hydroxylatio...

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Bibliographic Details
Main Authors: Annika Wahlström, Samer Al-Dury, Marcus Ståhlman, Fredrik Bäckhed, Hanns-Ulrich Marschall
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
FXR
Online Access:http://www.sciencedirect.com/science/article/pii/S240558081730002X