Antimycobacterial, Enzyme Inhibition, and Molecular Interaction Studies of Psoromic Acid in Mycobacterium tuberculosis: Efficacy and Safety Investigations

Antimycobacterial, Enzyme Inhibition, and Molecular Interaction Studies of Psoromic Acid in Mycobacterium tuberculosis: Efficacy and Safety Investigations

The current study explores the antimycobacterial efficacy of lichen-derived psoromic acid (PA) against clinical strains of Mycobacterium tuberculosis (M.tb). Additionally, the inhibitory efficacy of PA against two critical enzymes associated with M.tb, namely, UDP-galactopyranose mutase (UGM) and ar...

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Bibliographic Details
Main Authors: Sherif T. S. Hassan, Miroslava Šudomová, Kateřina Berchová-Bímová, Shanmugaraj Gowrishankar, Kannan R. R. Rengasamy
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Journal of Clinical Medicine
Subjects:
psoromic acid
arylamine N-acetyltransferase
UDP-galactopyranose mutase
antitubercular drug
drug resistance
drug design
Online Access:http://www.mdpi.com/2077-0383/7/8/226

Internet

http://www.mdpi.com/2077-0383/7/8/226

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