Autophagy Plays an Important Role in Anti-inflammatory Mechanisms Stimulated by Alpha7 Nicotinic Acetylcholine Receptor

Autophagy Plays an Important Role in Anti-inflammatory Mechanisms Stimulated by Alpha7 Nicotinic Acetylcholine Receptor

Alpha7 nicotinic acetylcholine receptor (α7nAChR) has been reported to alleviate neuroinflammation. Here, we aimed to determine the role of autophagy in α7nAChR-mediated inhibition of neuroinflammation and its underlying mechanism. Experimental autoimmune encephalomyelitis (EAE) mice and lipopolysac...

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Bibliographic Details
Main Authors: Bo-Zong Shao, Ping Ke, Zhe-Qi Xu, Wei Wei, Ming-He Cheng, Bin-Ze Han, Xiong-Wen Chen, Ding-Feng Su, Chong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Immunology
Subjects:
alpha7 nicotinic acetylcholine receptor
autophagy
neuroinflammation
experimental autoimmune encephalomyelitis
microglia
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00553/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00553/full

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