Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans.

Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans.

An ancestral polymorphic allele of the human autophagy-related gene IRGM1 is associated with altered gene expression and a genetic risk for Crohn's Disease (CD). We used the single nucleotide polymorphism rs10065172C/T as a marker of this polymorphic allele and genotyped 370 African American an...

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Bibliographic Details
Main Authors: Katherine Y King, Justin D Lew, Ngan P Ha, Jeffery S Lin, Xin Ma, Edward A Graviss, Margaret A Goodell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3025014?pdf=render

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http://europepmc.org/articles/PMC3025014?pdf=render

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