Immune-Complexome Analysis Identifies Immunoglobulin-Bound Biomarkers That Predict the Response to Chemotherapy of Pancreatic Cancer Patients

Immune-Complexome Analysis Identifies Immunoglobulin-Bound Biomarkers That Predict the Response to Chemotherapy of Pancreatic Cancer Patients

Pancreatic Ductal Adenocarcinoma (PDA) is an aggressive malignancy with a very poor outcome. Although chemotherapy (CT) treatment has poor efficacy, it can enhance tumor immunogenicity. Tumor-Associated Antigens (TAA) are self-proteins that are overexpressed in tumors that may induce antibody produc...

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Bibliographic Details
Main Authors: Giorgia Mandili, Laura Follia, Giulio Ferrero, Hiroyuki Katayama, Wang Hong, Amin A. Momin, Michela Capello, Daniele Giordano, Rosella Spadi, Maria Antonietta Satolli, Andrea Evangelista, Samir M. Hanash, Francesca Cordero, Francesco Novelli
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
proteomics
pancreatic cancer
chemotherapy
immune complexes
biomarkers
taa
computational analysis
Online Access:https://www.mdpi.com/2072-6694/12/3/746

Internet

https://www.mdpi.com/2072-6694/12/3/746

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