Stereoselectivity of isoflurane in adhesion molecule leukocyte function-associated antigen-1.

Isoflurane in clinical use is a racemate of S- and R-isoflurane. Previous studies have demonstrated that the effects of S-isoflurane on relevant anesthetic targets might be modestly stronger (less than 2-fold) than R-isoflurane. The X-ray crystallographic structure of the immunological target, leuko...

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Bibliographic Details
Main Authors: Weiming Bu, Luis M Pereira, Roderic G Eckenhoff, Koichi Yuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4011845?pdf=render