Prognostic significance of p53-expression in colorectal carcinoma as measured by a luminometric immunoassay

Background: Mutations of the TP53 gene induce the production of abnormal p53-protein with a prolonged half-life allowing its detection by monoclonal antibodies. In the following study we examined if elevated levels of p53 correlate with worse prognosis in colorectal cancer. Methods: We have quantifi...

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Bibliographic Details
Main Authors: Safi, Farouk, Amr, Amro, Lotter, Oliver
Format: Article
Language:deu
Published: German Medical Science GMS Publishing House 2010-01-01
Series:GMS German Medical Science
Subjects:
Online Access:http://www.egms.de/en/journals/gms/2010-8/000113.shtml