Synthesis, crystal structure and antiaromatase activity of 17-halo-16,17-seco-5-androstene derivatives
Starting from 3β-acetoxy-15-cyano-17-oxo-16,17-seco-5-androstene (2) and 3β-acetoxy- 15-cyano-17-hydroxy-17-methyl-16,17-seco-5-androstene (11), new 17-halo-derivatives (5–10 and 13) were obtained. The fluoro derivative 5 was obtained from 17-tosylate 4 in reaction with tetrabutylammonium fluoride....
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Serbian Chemical Society
2003-01-01
|
| Series: | Journal of the Serbian Chemical Society |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2003/0352-51390310707P.pdf |