Changes of blood-brain-barrier function and transfer of amyloid beta in rats with collagen-induced arthritis

Changes of blood-brain-barrier function and transfer of amyloid beta in rats with collagen-induced arthritis

Abstract Background Rheumatoid arthritis (RA) is characterized by synovial inflammation, cartilage damage, and systemic inflammation. RA is also associated with the occurrence of neuroinflammation and neurodegenerative diseases. In this study, the impacts of RA on the function of the blood-brain bar...

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Bibliographic Details
Main Authors: Po-Hsuan Lai, Ting-Hsuan Wang, Nai-You Zhang, Kuo-Chen Wu, Chung-Chen Jane Yao, Chun-Jung Lin
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Neuroinflammation
Subjects:
Collagen-induced arthritis
Blood-brain barrier
Amyloid beta
Receptor of advanced glycation end product
P-glycoprotein
Online Access:https://doi.org/10.1186/s12974-021-02086-2

Internet

https://doi.org/10.1186/s12974-021-02086-2

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