EsxA mainly contributes to the miR-155 overexpression in human monocyte-derived macrophages and potentially affect the immune mechanism of macrophages through miRNA dysregulation

EsxA mainly contributes to the miR-155 overexpression in human monocyte-derived macrophages and potentially affect the immune mechanism of macrophages through miRNA dysregulation

Abstracts: Background/purpose: Mycobacterium tuberculosis is a successful intracellular pathogen that uses multiple proteins to survive within macrophages, one of the most remarkable is the virulence factor EsxA. In this study, we evaluate the participation of EsxA in the miRNAs expression profile...

Full description

Bibliographic Details
Main Authors: Myrna Guadalupe Bonilla-Muro, Olga Nohemí Hernández de la Cruz, Juan Antonio Gonzalez-Barrios, Sofía Lizeth Alcaráz-Estrada, Mauricio Castañón-Arreola
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
EsxA
Macrophages
miRNA
PPI
Tuberculosis
Virulence
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118218300859

Internet

http://www.sciencedirect.com/science/article/pii/S1684118218300859

Similar Items