EsxA mainly contributes to the miR-155 overexpression in human monocyte-derived macrophages and potentially affect the immune mechanism of macrophages through miRNA dysregulation
Abstracts: Background/purpose: Mycobacterium tuberculosis is a successful intracellular pathogen that uses multiple proteins to survive within macrophages, one of the most remarkable is the virulence factor EsxA. In this study, we evaluate the participation of EsxA in the miRNAs expression profile...
Main Authors: | Myrna Guadalupe Bonilla-Muro, Olga Nohemí Hernández de la Cruz, Juan Antonio Gonzalez-Barrios, Sofía Lizeth Alcaráz-Estrada, Mauricio Castañón-Arreola |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-04-01
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Series: | Journal of Microbiology, Immunology and Infection |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1684118218300859 |
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