Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging
Abstract Skin aging is driven by intrinsic and extrinsic factors impacting on skin functionality with progressive age. One factor of this multifaceted process is cellular senescence, as it has recently been identified to contribute to a declining tissue functionality in old age. In the skin, senesce...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-03-01
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Series: | npj Aging and Mechanisms of Disease |
Online Access: | https://doi.org/10.1038/s41514-020-0042-x |