Th2-polarised PrP-specific transgenic T-cells confer partial protection against murine scrapie.
Several hurdles must be overcome in order to achieve efficient and safe immunotherapy against conformational neurodegenerative diseases. In prion diseases, the main difficulty is that the prion protein is tolerated as a self protein, which prevents powerful immune responses. Passive antibody therapy...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-09-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC3164648?pdf=render |