Argemone mexicana extract alleviates gastrointestinal disorders by stimulating muscarinic receptors and blocking voltage-gated L-type calcium channels

Argemone mexicana extract alleviates gastrointestinal disorders by stimulating muscarinic receptors and blocking voltage-gated L-type calcium channels

Objective: To investigate the pharmacological potential of Argemone mexicana in treating constipation and emesis by using in vitro and in vivo models. Methods: The spasmogenic and spasmolytic effects were evaluated on isolated rabbit jejunum fragments loaded in a tissue organ bath. The response was...

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Bibliographic Details
Main Authors: Rabia Iqbal, Irfan Hamid, Khalid Hussain Janbaz, Muhammad Furqan Akhtar, Ammara Saleem, Ali Sharif, Sohaib Peerzada, Bushra Akhtar, Kashif Sohail, Sajid Ali
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
argemone mexicana; muscarinic agonist; calcium channel blocker; constipation; emesis
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=5;spage=214;epage=221;aulast=Iqbal

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=5;spage=214;epage=221;aulast=Iqbal

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