Pró-fármaco ativado por enzima, uma estratégia promissora na quimioterapia

Strategies that promote selective activation of prodrugs by enzymes can be divided into two major classes: 1) deliver of a monoclonal antibody-enzyme immunoconjugate that can recognize a specific antigen and promote the prodrug to a citotoxic drug, with a high selectivity for the target cells, and 2...

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Bibliographic Details
Main Authors: Lorena Blau, Renato Farina Menegon, Man Chin Chung
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2006-12-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422006000600028&lng=en&tlng=en