Mass Spectrometry-Based Proteomics Approach Characterizes the Dual Functionality of miR-328 in Monocytes

Mass Spectrometry-Based Proteomics Approach Characterizes the Dual Functionality of miR-328 in Monocytes

MicroRNAs (miRs) are small noncoding RNAs which control the expression of target genes by either translational repression or RNA degradation, known as canonical miR functions. The recent discovery that miR-328 has a noncanonical function and can activate gene expression by antagonizing the activity...

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Bibliographic Details
Main Authors: Meike J. Saul, Anett B. Hegewald, Anne C. Emmerich, Elena Ossipova, Marc Vogel, Isabell Baumann, Kim Kultima, Johan Lengqivst, Dieter Steinhilber, Per Johan Jakobsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Pharmacology
Subjects:
miR-328
noncanonical miR function
proteomics
TLR2
NOX2
p53
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00640/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.00640/full

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