The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer

<p>Abstract</p> <p>Background</p> <p>Qualitative and quantitative changes in human mitochondrial DNA (mtDNA) have been implicated in various cancer types. A 4,977 bp deletion in the major arch of the mitochondrial genome is one of the most common mutations associated wi...

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Bibliographic Details
Main Authors: Li Hongzhi, Jiang Yulin, Xin Yijuan, Wei Xiaosong, Jin Tao, Nie Hezhongrong, Fang Hezhi, Shen Lijun, He Jing, Chen Tao, Chen Guorong, Lu Jianxin, Bai Yidong
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/12/8