Investigating the role of ceramide metabolism-associated CERS5 (LASS5) gene in atherosclerosis pathogenesis in endothelial cells

Objective: Ceramide, the backbone of sphingolipids, is the key component affecting atherosclerotic changes through its important second-messenger role. Previous studies have demonstrated protective role of AMP-activated protein kinase (AMPK) genes in regulating atherosclerosis and hypertension. Cera...

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Bibliographic Details
Main Authors: Neslihan Çoban, Filiz Güçlü Geyik, Özlem Yıldırım, Nihan Erginel Ünaltuna
Format: Article
Language:English
Published: KARE Publishing 2017-03-01
Series:Türk Kardiyoloji Derneği Arşivi
Subjects:
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-82389