Nuclear Respiratory Factor 1 Acting as an Oncoprotein Drives Estrogen-Induced Breast Carcinogenesis

Nuclear Respiratory Factor 1 Acting as an Oncoprotein Drives Estrogen-Induced Breast Carcinogenesis

We have previously shown nuclear respiratory factor 1 (NRF1)-mediated transcriptional programming of mitobiogenesis contributes to estrogen-induced breast cancer through modulating cell cycle progression. In this study, we report a new role of NRF1 that goes beyond that of programming mitobiogenesis...

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Bibliographic Details
Main Authors: Jayanta K. Das, Quentin Felty, Robert Poppiti, Robert M. Jackson, Deodutta Roy
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cells
Subjects:
estrogen
breast cancer stem cell
NRF1
oncoprotein
re-programming
Online Access:https://www.mdpi.com/2073-4409/7/12/234

Internet

https://www.mdpi.com/2073-4409/7/12/234

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