MiR-425 expression profiling in acute myeloid leukemia might guide the treatment choice between allogeneic transplantation and chemotherapy

MiR-425 expression profiling in acute myeloid leukemia might guide the treatment choice between allogeneic transplantation and chemotherapy

Abstract Background Acute myeloid leukemia (AML) is a highly heterogeneous disease. MicroRNAs function as important biomarkers in the clinical prognosis of AML. Methods This study identified miR-425 as a prognostic factor in AML by screening the TCGA dataset. A total of 162 patients with AML were en...

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Bibliographic Details
Main Authors: Chen Yang, Tingting Shao, Huihui Zhang, Ninghan Zhang, Xiaoying Shi, Xuejiao Liu, Yao Yao, Linyan Xu, Shengyun Zhu, Jiang Cao, Hai Cheng, Zhiling Yan, Zhenyu Li, Mingshan Niu, Kailin Xu
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Translational Medicine
Subjects:
miR-425
Acute myeloid leukemia
Prognosis
Chemotherapy
Allo-HSCT
Online Access:http://link.springer.com/article/10.1186/s12967-018-1647-8

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http://link.springer.com/article/10.1186/s12967-018-1647-8

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