β-Lactamase Tools for Establishing Cell Internalization and Cytosolic Delivery of Cell Penetrating Peptides

β-Lactamase Tools for Establishing Cell Internalization and Cytosolic Delivery of Cell Penetrating Peptides

The ability of cell penetrating peptides (CPPs) to deliver biologically relevant cargos into cells is becoming more important as targets in the intracellular space continue to be explored. We have developed two assays based on CPP-dependent, intracellular delivery of TEM-1 β-lactamase enzym...

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Bibliographic Details
Main Authors: Shane R. Stone, Tatjana Heinrich, Suzy M. Juraja, Jiulia N. Satiaputra, Clinton M. Hall, Mark Anastasas, Anna D. Mills, Christopher A. Chamberlain, Scott Winslow, Kristin Priebatsch, Paula T. Cunningham, Katrin Hoffmann, Nadia Milech
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Biomolecules
Subjects:
cell penetrating peptide
high-throughput screening
functional validation
cell internalization
cytosolic delivery
Online Access:http://www.mdpi.com/2218-273X/8/3/51

Internet

http://www.mdpi.com/2218-273X/8/3/51

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