Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling Epilepsy-Induced Hippocampal Endoplasmic Reticulum Stress and Oxidative Damage

Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling Epilepsy-Induced Hippocampal Endoplasmic Reticulum Stress and Oxidative Damage

Epilepsy is one of the most common chronic neurological disorders which provoke progressive neuronal degeneration. Endoplasmic reticulum (ER) stress has recently been recognized as pivotal etiological factors contributing to epilepsy-induced neuronal damage. However, the specific contribution of epi...

Full description

Bibliographic Details
Main Authors: Xinjian Zhu, Jingde Dong, Bing Han, Rongrong Huang, Aifeng Zhang, Zhengrong Xia, Huanhuan Chang, Jie Chao, Honghong Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neuronal nitric oxide synthase
epilepsy
oxidative damage
ER stress
peroxynitrite
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00377/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00377/full

Similar Items