Estrogens Correlate with PELP1 Expression in ER Positive Breast Cancer.

The Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) is an estrogen receptor (ER) coactivator and a proto-oncogene known to be deregulated in endocrine cancers. In breast cancer, PELP1 overexpression has been associated with endocrine therapy resistance. Although PELP1 is known to be regu...

Full description

Bibliographic Details
Main Authors: Marianne Hauglid Flågeng, Stian Knappskog, Jennifer Gjerde, Per Eystein Lønning, Gunnar Mellgren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4527840?pdf=render