The mechanism of poly-galloyl-glucoses preventing Influenza A virus entry into host cells.

Hemagglutinin (HA) is essential for Influenza A virus infection, but its diversity of subtypes presents an obstacle to developing broad-spectrum HA inhibitors. In this study, we investigated the molecular mechanisms by which poly-galloyl glucose (pGG) analogs inhibit influenza hemagglutinin (HA) in...

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Bibliographic Details
Main Authors: Hu Ge, Ge Liu, Yang-Fei Xiang, Yu Wang, Chao-Wan Guo, Nan-Hao Chen, Ying-Jun Zhang, Yi-Fei Wang, Kaio Kitazato, Jun Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24718639/pdf/?tool=EBI