Adenovirus dodecahedron, as a drug delivery vector.

BACKGROUND:Bleomycin (BLM) is an anticancer antibiotic used in many cancer regimens. Its utility is limited by systemic toxicity and dose-dependent pneumonitis able to progress to lung fibrosis. The latter can affect up to nearly 50% of the total patient population, out of which 3% will die. We prop...

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Bibliographic Details
Main Authors: Monika Zochowska, Agnieszka Paca, Guy Schoehn, Jean-Pierre Andrieu, Jadwiga Chroboczek, Bernard Dublet, Ewa Szolajska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2679213?pdf=render