A survey of new temperature-sensitive, embryonic-lethal mutations in C. elegans: 24 alleles of thirteen genes.

To study essential maternal gene requirements in the early C. elegans embryo, we have screened for temperature-sensitive, embryonic lethal mutations in an effort to bypass essential zygotic requirements for such genes during larval and adult germline development. With conditional alleles, multiple e...

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Bibliographic Details
Main Authors: Sean M O'Rourke, Clayton Carter, Luke Carter, Sara N Christensen, Minh P Jones, Bruce Nash, Meredith H Price, Douglas W Turnbull, Aleena R Garner, Danielle R Hamill, Valerie R Osterberg, Rebecca Lyczak, Erin E Madison, Michael H Nguyen, Nathan A Sandberg, Noushin Sedghi, John H Willis, John Yochem, Eric A Johnson, Bruce Bowerman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3046959?pdf=render