The effect of bacterial recombination on adaptation on fitness landscapes with limited peak accessibility.

There is ample empirical evidence revealing that fitness landscapes are often complex: the fitness effect of a newly arisen mutation can depend strongly on the allelic state at other loci. However, little is known about the effects of recombination on adaptation on such fitness landscapes. Here, we...

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Bibliographic Details
Main Authors: Danesh Moradigaravand, Jan Engelstädter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3487459?pdf=render