Nanosecond pulsed electric fields enhance mesenchymal stem cells differentiation via DNMT1-regulated OCT4/NANOG gene expression

Nanosecond pulsed electric fields enhance mesenchymal stem cells differentiation via DNMT1-regulated OCT4/NANOG gene expression

Abstract Background Multiple strategies have been proposed to promote the differentiation potential of mesenchymal stem cells (MSCs), which is the fundamental property in tissue formation and regeneration. However, these strategies are relatively inefficient that limit the application. In this study...

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Bibliographic Details
Main Authors: Kejia Li, Tong Ning, Hao Wang, Yangzi Jiang, Jue Zhang, Zigang Ge
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Nanosecond pulsed electric fields
Demethylation
DNMT1
Biophysical stimulation
Stem cell differentiation
Online Access:http://link.springer.com/article/10.1186/s13287-020-01821-5

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http://link.springer.com/article/10.1186/s13287-020-01821-5

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