Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors

Systemic mastocytosis (SM) is a rare clonal hematologic neoplasm, driven, in almost all cases, by the activating <i>KIT</i> D816V mutation that leads to the growth and accumulation of neoplastic mast cells. While patients with advanced forms of SM have a poor prognosis, the introduction...

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Bibliographic Details
Main Authors: William Shomali, Jason Gotlib
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/6/2983